| CAS No.: | 121062-08-6 |
|---|---|
| Formula: | C50h69n15o9 |
| EINECS: | Tanning Peptides |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Technical |
| Samples: |
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| Customization: |
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Product Information
Products Name: Melanotan II
CAS No.: 121062-08-6
Purity: >99.0%
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.2g/mol
Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2
Appearance: White Lyophilized powder
Reconstitution: Required
Storage:After reconstitution store at 2°C - 8°C
Description:
What is Melanotan II?
Melanotan II (CAS NO.121062-08-6) was first synthesized at the University of Arizona. Researchers decided to find a more potent and stable alternative, one that would be more practical to defend against skin cancer.
The researchers headed by Victor Hruby found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH after synthesizing and
screening hundreds of molecules. They dubbed this new peptide, "Melanotan" (later Melanotan I, now known as afamelanotide). They subsequently developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they named "Melanotan Acetate".
Since their discovery, numerous studies dating back to the mid-1980s have found no obvious toxic effects of the Melanotan peptides. The scientists hoped to use Melanotan peptides to combat melanoma by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.
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